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M 16209

SKU: orb3173710

Description

M 16209 is an orally active aldose reductase (AR) inhibitor. It effectively inhibits partially purified aldose reductase from various sources, with IC50 values of 0.12 μM for rat lens AR, 0.24 μM for bovine lens AR, 4.5 μM for bovine kidney AR, 1.2 μM for canine lens AR, and 9.3 μM for human placental AR. M 16209 is applicable in the study of metabolic diseases such as diabetes.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number128851-36-5
MW359.15
FormulaC11H7BrN2O5S
SMILESO=C1NC(=O)CN1S(=O)(=O)C=2OC=3C=CC=CC3C2Br
TargetReductase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information