LZ-007

• Catalog Number: orb2814662
• Category: Small Molecules
• Description: LZ-007 is an agonist of the Farnesoid X receptor (FXR), with an EC50 of 51 nM as determined by TR-FRET assay, and an EC50 of 76 nM in HepG2 cells. It exhibits favorable pharmacokinetic properties in SD rats and can improve metabolic dysfunction-associated steatohepatitis induced by high-fat diets and CCl4 in mice.
• MW: 518.53
• CAS Number: 2920000-23-1
• Formula: C₂₇H₂₉F₃N₂O₅
• SMILES: O=C(O)C1=CC=C(OCC2CCN(CC=3C(=NOC3C(C)C)C=4C=CC=CC4OC(F)(F)F)CC2)C=C1
• Storage: -20°C
• Note: For research use only