LZ-007

SKU: orb2814662

Description

LZ-007 is a potent FXR agonist, demonstrating EC50 values of 51 nM in TR-FRET and 76 nM in HepG2 cells. It shows favorable pharmacokinetics in rats and has been shown to ameliorate diet- and CCl4-induced metabolic dysfunction-associated steatohepatitis in mouse models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2920000-23-1
• MW: 518.53
• Formula: C₂₇H₂₉F₃N₂O₅
• SMILES: O=C(O)C1=CC=C(OCC2CCN(CC=3C(=NOC3C(C)C)C=4C=CC=CC4OC(F)(F)F)CC2)C=C1
• Target: FXR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

175359111