[Lys5,MeLeu9,Nle10]-NKA(4-10)

SKU: orb1296469

Description

This compound is a highly selective and potent agonist of the NK2 receptor, exhibiting an IC50 of 6.1 nM. It effectively induces smooth muscle contraction in isolated rat fundus and bladder tissues, with EC50 values of 117 nM and 10 nM, respectively. This makes it a valuable research tool for studying tachykinin receptor function in gastrointestinal and urogenital systems.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 137565-28-7
• MW: 803.99
• Purity: >99.99% (May vary between batches)
• Formula: C₃₉H₆₅N₉O₉
• SMILES: [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCCN)=O)C(N[C@H](C(NCC(N([C@H](C(N[C@@H](CCCC)C(N)=O)=O)CC(C)C)C)=O)=O)C(C)C)=O
• Target: Neurokinin receptor
• Solubility: H2O:1 mg/mL (1.24 mM)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tachykinin receptor, Neurokinin receptor, Neurokininreceptor, Neurokinin Receptor, NK receptor, NK2, inhibit, Inhibitor, [Lys5,MeLeu9,Nle10] NKA(4 10), [Lys5,MeLeu9,Nle10]-NKA, [Lys5,MeLeu9,Nle10]NKA(410), [Lys-5,MeLeu9,Nle10]-NKA(4-10)

Compound Identifiers

PubChem CID

10417908