Lyn-IN-1

SKU: orb1309458

Description

Lyn-IN-1, an analog of Bafetinib, is a potent and selective dual kinase inhibitor targeting both Bcr-Abl and Lyn. It is utilized in biochemical and cellular research, particularly in studies of chronic myeloid leukemia (CML), demonstrating activity in both in vitro assays and in vivo models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 887650-05-7
• MW: 576.62
• Purity: 99.33% (May vary between batches)
• Formula: C₃₀H₃₁F₃N₈O
• SMILES: CN(C)[C@H]1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(Nc3ncc(cn3)-c3cncnc3)c2)C1
• Target: Src,Bcr-Abl
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.47 mM);DMSO:45 mg/mL (78.04 mM)

Storage & Handling

• Storage: keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bcr-Abl, BcrAbl, Bafetinib, Bafetinib analog, LynIN1, Lyn-IN-1, Lyn IN 1, Lyn, Inhibitor, inhibit

Compound Identifiers

PubChem CID

24853523