LY3381916

SKU: orb1309461

Description

LY3381916 is a potent and selective brain-penetrant small molecule inhibitor of IDO1. It uniquely targets the apo-form of the enzyme prior to heme incorporation. This tool compound is used in both in vitro and in vivo research to investigate immunomodulation and cancer immunotherapy pathways.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2166616-75-5
• MW: 396.45
• Purity: 99.30% (May vary between batches)
• Formula: C₂₃H₂₅FN₂O₃
• SMILES: C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2N(CCc2c1)C(=O)C1CCOCC1
• Target: IDO,Indoleamine 2,3-Dioxygenase (IDO)
• Solubility: DMSO:300 mg/mL (756.72 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.61 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Indoleamine2,3Dioxygenase, Indoleamine 2,3-Dioxygenase (IDO), Indoleamine2,3Dioxygenase(IDO), Indoleamine 2,3Dioxygenase (IDO), Indoleamine 2,3-Dioxygenase, inhibit, IDO, IDO1, IDO1 IN 5, IDO1IN5, IDO-1-IN-5, IDO1-IN-5, Inhibitor

Compound Identifiers

PubChem CID

132209614