LY309887

SKU: orb1707038

Description

LY309887 is a potent small molecule inhibitor of glycinamide ribonucleotide formyltransferase (GARFT) with a Ki of 6.5 nM, exhibiting antitumor properties. It is utilized in cancer research to study purine biosynthesis inhibition and has demonstrated activity in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 127228-54-0
• MW: 449.48
• Formula: C₁₉H₂₃N₅O₆S
• SMILES: Nc1nc2NC[C@H](CCc3ccc(s3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)Cc2c(=O)[nH]1
• Target: LTR,Antifolate

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135430850