LY2979165

SKU: orb1940714

Description

LY2979165 is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.(In Vivo):LY2979165 reduces BOLD signal and increases plasma levels of 2812223 in vivo.

Key Properties

• CAS Number: 1311385-32-6
• MW: 390.42
• Purity: >98% (HPLC)
• Formula: C₁₃H₂₂N₆O₆S
• SMILES: N.O.C[C@H](N)C(=O)N[C@]1(C[C@@H](Sc2ncn[nH]2)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
• Target: GluR
• Solubility: In Vitro: H2O : ≥ 50 mg/mL (128.07 mM)D)

Bioactivity

• In Vivo:
  LY2979165 attenuated the ketamine-evoked BOLD phMRI signal In vivo.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

mGlu2 agonist

Quick Database Links

Gene Symbol

GluR