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LY2090314

SKU: orb1224501

Description

LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. Phase 2.

Images & Validation

Key Properties

CAS Number603288-22-8
MW512.53
Purity>98% (HPLC)
FormulaC28H25FN6O3
SMILESO=C(C(C1=CN2C3=C1C=C(F)C=C3CN(C(N4CCCCC4)=O)CC2)=C5C6=CN=C7C=CC=CN76)NC5=O
TargetGSK-3
SolubilityEthanol: 2 mg/mL warmed (3.9 mM); DMSO: 100 mg/mL (195.11 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

LY2090314 | LY-2090314 | LY 2090314.

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    603288-22-8

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    C28H25FN6O3

    5 mg, 50 mg, 100 mg, 2 mg, 1 mg, 200 mg, 10 mg, 25 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

LY2090314 (orb1224501)

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Available Sizes

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200 mg
500 mg
2 mg
$ 110.00
5 mg
$ 160.00
10 mg
$ 230.00
25 mg
$ 390.00
50 mg
$ 610.00
100 mg
$ 890.00