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    LY-411575

    LY-411575

    Catalog Number: orb1301106

    DispatchUsually dispatched within 3-5 working days
    $ 689.00
    Catalog Numberorb1301106
    CategorySmall Molecules
    DescriptionLY-411575
    CAS Number209984-57-6
    Purity99.38%
    MW479.48
    SMILESN(C([C@@H](NC([C@@H](O)C1=CC(F)=CC(F)=C1)=O)C)=O)[C@H]2C=3C(C=4C(N(C)C2=O)=CC=CC4)=CC=CC3
    FormulaC26H23F2N3O4
    Biological ActivityLY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.
    NoteFor research use only
    Expiration Date12 months from date of receipt.
    • LY-411575 [orb146231]

      [209984-57-6]

      479.4753

      C26N3O4F2H23

      1 g, 100 mg, 250 mg, 10 mM * 1 mL in DMSO
    • Deshydroxy LY-411575 [orb419535]

      ≥98%

      209984-56-5

      463.48

      C26H23F2N3O3

      1 mg, 25 mg, 5 mg
    • LY-411575 [orb1225693]

      > 98% (HPLC)

      209984-57-6

      100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 2 mg, 1 g, 500 mg, 200 mg
    • LY-411575 isomer 1 [orb1709228]

      98%

      209984-58-7

      479.48

      C26H23F2N3O4

      25 mg, 100 mg, 50 mg
    • LY-411575 (isomer 3) [orb1686890]

      98%

      479.48

      C26H23F2N3O4

      2 mg, 1 mg
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