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Catalog Number | orb1301106 |
---|---|
Category | Small Molecules |
Description | LY-411575 |
CAS Number | 209984-57-6 |
Purity | 99.38% |
MW | 479.48 |
SMILES | N(C([C@@H](NC([C@@H](O)C1=CC(F)=CC(F)=C1)=O)C)=O)[C@H]2C=3C(C=4C(N(C)C2=O)=CC=CC4)=CC=CC3 |
Formula | C26H23F2N3O4 |
Biological Activity | LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
209984-57-6 |
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