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LXG6403

SKU: orb3027407

Description

LXG6403 is a powerful dual-thiazole LOX cell activity inhibitor with an IC50 of 1.3 μM. It exhibits anticancer properties by restructuring the extracellular matrix, enhancing the penetration of chemotherapeutic drugs, inducing reactive oxygen species (ROS) production, and promoting cell death mediated by DNA damage, thereby overcoming chemotherapy resistance in triple-negative breast cancer.

Research Area

Cardiovascular Research, Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number315705-04-5
MW345.44
FormulaC15H15N5OS2
SMILESO=C(NC1=CC=C(C=C1)NC2=NC(=CS2)C=3SC(=NC3C)N)C
TargetROS,FAK,Lipoxygenase,Apoptosis,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information