LWG-301

SKU: orb1744152

Description

LWG-301 is a potent, allosteric GLS1 inhibitor (IC50 = 7 nM) that disrupts glutamine metabolism, elevating ROS to induce apoptosis. It has demonstrated moderate antitumor activity in HCT116 xenograft models, supporting its use in cancer metabolism research both in vitro and in vivo.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• MW: 566.72
• Formula: C₂₈H₃₈N₈O₃S
• SMILES: CCCCC(=O)NC1=NN=C(S1)NC2CCN(CC2)C3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OCCCC
• Target: Glutaminase,Others,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166642411