LTX-315

SKU: orb1226499

Description

LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis; triggers immunogenic cell death, induces cell death and DAMP release by mitochondria distortion in human melanoma cells.Breast Cancer Phase 2 Clinical.

Key Properties

• CAS Number: 1345407-05-7
• MW: 1439.823
• Purity: >98% (HPLC)
• Formula: C₇₈H₁₀₆N₁₈O₉
• SMILES: NCCCC[C@@H](C(N)=O)NC([C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CC7=CNC8=C7C=CC=C8)NC([C@H](CCCCN)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O
• Target: Others
• Solubility: Ethanol: 100 mg/mL (69.45 mM); DMSO: <1 mg/mL; Water: 100 mg/mL (69.45 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Oncopore

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