LTB

SKU: orb2814293

Description

LTB is a self-assembling prodrug nanoplatform formed by conjugating Lonidamine and BMS-1. It encapsulates the photosensitizer Chlorin e6 (Ce6) to create LTB-6 NPs, enabling co-delivery for combined photodynamic therapy and immune checkpoint blockade in cancer research, as studied in preclinical models.

Research Area

Cancer Biology, Cell Biology, Immunology & Inflammation

Images & Validation

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Key Properties

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MW	985.09
Formula	C₅₃H₅₉Cl₂N₃O₇S₂
Target	PD-1/PD-L1

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

PD-1/PD-L1

Protocol Information

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Reactivity:	Mouse
Dynamic Range:	15.63-1000 pg/mL
Sensitivity:	6.5 pg/mL

Reactivity:	Human
Dynamic Range:	15.63-1000 pg/mL
Sensitivity:	6.2 pg/mL

Reactivity:	Rat
Dynamic Range:	15.63-1000 pg/mL
Sensitivity:	6.3 pg/mL

Reactivity:	Human
Dynamic Range:	15.63-1000pg/mL
Sensitivity:	9.38 pg/mL

Applications:	ELISA, IF, WB
Reactivity:	Human, Mouse
Clonality:	Polyclonal
Conjugation:	Unconjugated

LTB

Description

Research Area

Images & Validation

Key Properties

Storage & Handling

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