LTA4H-IN-5

SKU: orb3134835

Description

LTA4H-IN-5 (Compound H122) is an orally active inhibitor of leukotriene A4 hydrolase (LTA4H), effectively suppressing both its aminopeptidase and hydrolase activities with IC50 values of 0.38 nM and 16.93 nM, respectively. In C57 mice, it demonstrates favorable pharmacokinetic properties and shows efficacy in improving DNBS-induced ulcerative colitis in rat models.

Research Area

Metabolism Research

Key Properties

• Formula: C₁₈H₁₇Cl₂FN₄O₄
• Target: Aminopeptidase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Aminopeptidase