LSD1/HDAC6-IN-2

SKU: orb2664402

Description

JBI-802 is a potent, orally bioavailable small molecule inhibitor targeting LSD1, HDAC6, and HDAC8 with respective IC₅₀ values of 50 nM, 11 nM, and 98 nM. It shows selectivity over MAOs and exhibits antiproliferative effects in vitro against hematological and solid tumor cell lines, supporting its investigation in oncology research.

Research Area

Epigenetics & Chromatin, Metabolism Research, Metabolism Research; Epigenetics & Chromatin, Molecular Biology, Neuroscience

Key Properties

• CAS Number: 2982787-50-6
• MW: 443.34
• Formula: C₂₁H₂₃BrN₄O₂
• SMILES: N(CC1=CN(CC2=CC=C(C(NO)=O)C=C2)N=C1)[C@H]3[C@@H](C3)C4=CC=CC=C4.Br
• Target: HDAC,MAO

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166177211