LSD1-IN-48

SKU: orb3211141

Description

LSD1-IN-48 is a cyclopropylamine-pyrimidine derivative and a highly selective LSD1 inhibitor with an IC50 of 7.87 nM against human targets. It elevates H3K4me1/2 histone methylation levels and induces apoptosis, upregulates CD86, downregulates SOX2 and CD44, and inhibits cancer cell proliferation. LSD1-IN-48 is applicable for research in acute myeloid leukemia.

Key Properties

• CAS Number: 3104325-26-7
• MW: 436.44
• Formula: C₁₈H₁₈F₂N₆O₃S
• SMILES: N(CC1=CN(N=N1)C2=NC(S(C)(=O)=O)=NC(OC)=C2)[C@H]3[C@@H](C3)C4=C(F)C=C(F)C=C4
• Target: Apoptosis,Histone Demethylase,Immunology/Inflammation related

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,Histone Demethylase,Immunology/Inflammation related