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LSD1-IN-43

SKU: orb3135257

Description

LSD1-IN-43 is a highly selective, reversible, and orally active LSD1 inhibitor with blood-brain barrier permeability, showing an IC50 value of 0.8 μM. It exhibits lower inhibitory activity against LSD1 homologs MAO-A and MAO-B. LSD1-IN-43 significantly inhibits Aβ aggregation and enhances neuronal cell viability induced by Aβ. It is applicable in Alzheimer's disease (AD) research.

Research Area

Epigenetics & Chromatin, Metabolism Research, Neuroscience

Images & Validation

Key Properties

TargetBeta Amyloid,Histone Demethylase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information