LSD1-IN-27

SKU: orb1905837

Description

LSD1-IN-27 is a potent lysine-specific demethylase 1 inhibitor (IC50 = 13 nM) that suppresses cancer cell stemness, migration, and PD-L1 expression in vitro. It enhances anti-tumor T-cell responses, making it a valuable tool for immuno-oncology research in gastric cancer models.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 2904571-94-2
• MW: 355.48
• Purity: 99.98% (May vary between batches)
• Formula: C₂₄H₂₅N₃
• SMILES: N(C=1C2=C(N=C3C1C=C(C)C=C3)C(C)=C(C)C=C2)C4=CC=C(N(C)C)C=C4
• Target: Histone Demethylase,PD-1/PD-L1
• Solubility: DMSO:16.67 mg/mL (46.89 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.63 mM)

Bioactivity

• Target IC50:
  LSD1:13 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Histone Demethylase, HistoneDemethylase, PD1/PDL1, PD1, PD-1, LSD1IN27, LSD1-IN-27, LSD1, PDL1, PD-L1

Compound Identifiers

PubChem CID

168510569