LpxH-IN-3

SKU: orb3211326

Description

LpxH-IN-3 is an inhibitor of Klebsiella pneumoniae (Klebsiella pneumoniae) LpxH, with an IC50 of 0.17 μM. It binds to the L-type hydrophobic binding pocket of LpxH in Klebsiella pneumoniae, forming hydrogen bonds and interacting with key residues, thereby disrupting lipid A biosynthesis and inducing bacterial death. LpxH-IN-3 exhibits moderate antibacterial activity against Klebsiella pneumoniae and Escherichia coli. This compound can be utilized in studies related to Klebsiella pneumoniae infections.

Key Properties

• Target: Antibacterial

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Antibacterial