Lonitoclax

SKU: orb2944352

Description

Lonitoclax is a potent Bcl-2 inhibitor with antitumor efficacy comparable to venetoclax in preclinical models. It is a research tool for studying relapsed/refractory CLL, SLL, and low-grade lymphomas, with applications in both in vitro cellular assays and in vivo xenograft studies.

Research Area

Cell Biology

Key Properties

• CAS Number: 2952589-57-8
• MW: 733.294
• Formula: C₄₃H₄₅ClN₄O₅
• SMILES: C(=O)(C1=C(C=C(Cl)C=C1)C2=CC(C(N(CC3=C(C)C(OC)=CC=C3)C4=CC=C(O)C=C4)=O)=C(C)N2C)N5[C@H](CN6CCOCC6)CC=7C(C5)=CC=CC7
• Target: Bcl-2 Family

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168969724