Lonicerin

SKU: orb1297300

Description

Lonicerin is a bioactive flavonoid with demonstrated antioxidant, anti-arthritic, and antifungal properties. Its multi-target activity makes it a candidate for research into combination therapies against complex infections like Candida albicans-induced fungal arthritis, as investigated in various in vitro and in vivo models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 25694-72-8
• MW: 594.52
• Purity: 99.96%
• Formula: C₂₇H₃₀O₁₅
• SMILES: C[C@@H]1O[C@@H](O[C@H]2[C@H](Oc3cc(O)c4c(c3)oc(cc4=O)-c3ccc(O)c(O)c3)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
• Target: Antibacterial,Xanthine Oxidase,Antifungal,Apoptosis,Endogenous Metabolite
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.36 mM);DMSO:60 mg/mL (100.92 mM)

Bioactivity

• In Vitro:
  The hypothesis is that upon reaction with 1,1-diphenyl-2-picrylhydrazyl (DPPH), the peak areas (PAs) of compounds with potential antioxidant effects in the HPLC chromatograms will be significantly reduced or disappeared, and the identity confirmation could be achieved by HPLC-DAD-TOF/MS hyphenated technique. Using the proposed approach, about 14 compounds in the FLJ extract were found to possess a potential antioxidant activity. They were identified as chlorogenic acid (1), 1-O-caffeoylquinic acid (1-O-CQA, 2), caffeic acid (4), 4-O-CQA (5), rutin (7), isoquercitrin (8), luteolin-7-O-glucoside (9), Lonicerin (10), 4,5-O-dicaffeoylquinic acid (4,5-O-diCQA, 11), 3,5-O-diCQA (12), 1,3-O-diCQA (13), 3,4-O-diCQA (14), 1,4-O-diCQA (16), and luteolin (17). In addition, the free radical scavenging capacities of the available identified compounds were also investigated by HPLC assay.

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Antifection, Apoptosis, algE, Alginate, Inhibitor, Lonicerin, inhibit, secretion, P. aeruginosa, protein

Compound Identifiers

PubChem CID

5282152