LNK2-S

SKU: orb2802373

Description

LNK2-S is a cleavable linker-toxin conjugate, specifically linking the potent topoisomerase I inhibitor Exatecan, for the construction of antibody-drug conjugates (ADCs). It is a key intermediate used in research for developing and evaluating novel ADC therapeutics in both in vitro and in vivo experimental models.

Key Properties

• CAS Number: 2983134-61-6
• MW: 1970.93
• Formula: C₈₇H₁₁₂FN₁₉O₃₃
• SMILES: N(C(O[C@H](CNC(CC[C@@H](C(N(CC(N(CC(N(CC(N(CC(N(CC(N(CC(N(CC(N(CC(N(CC(N(CC(N)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)NC(COCCOCCNC(CCN1C(=O)C=CC1=O)=O)=O)=O)C2=CC(N(=O)=O)=C(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)C=C2)=O)[C@@H]4C5=C6C(C=7N(C6)C(=O)C8=C(C7)[C@](CC)(O)C(=O)OC8)=NC=9C5=C(CC4)C(C)=C(F)C9
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176282581