LMP-420

SKU: orb3173128

Description

LMP-420 is a selective inhibitor of tumor necrosis factor-α (TNF-α). It reduces the release of pro-inflammatory cytokines, such as IL-1β and IL-2, while inducing the expression of anti-inflammatory cytokine IL-10, and anti-apoptotic molecules SOCS-1 and Mn-SOD. LMP-420 also downregulates chemokines like IP-10 and MCP-1, which decreases immune cell infiltration. This compound shows potential for research into type 1 diabetes, inflammatory diseases such as colitis, and HIV-mycobacterium tuberculosis co-infection.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 473870-63-2
• MW: 283.52
• Formula: C₁₀H₁₅BClN₅O₂
• SMILES: ClC1=NC(=NC2=C1N=CN2CCCCCB(O)O)N
• Target: Interleukin,TNF

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Interleukin,TNF