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LMB-100

SKU: orb3027798

Description

LMB-100 is a human immunotoxin targeting MSLN/Mesothelin, known for inducing systemic inflammatory response and recruitment of CD8 T cells. It enhances the antitumor effects of anti-PD-1 antibodies in murine models of mesothelioma with human peripheral blood mononuclear cell transplants and syngeneic lung adenocarcinoma expressing mesothelin. LMB-100 is useful for mesothelioma research. Recommended isotype control: Fab Fused with a fragment of Pseudomonas exotoxin A.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

TargetMesothelin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

LMB-100 (orb3027798)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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