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Catalog Number | orb1302882 |
---|---|
Category | Small Molecules |
Description | LM10 |
Purity | 99.88% |
MW | 229.21 |
Biological Activity | Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable. |
CAS Number | 1316695-35-8 |
Formula | C11H8FN5 |
SMILES | Fc1ccc2c(\C=C\c3nnn[nH]3)c[nH]c2c1 |
Storage | -20°C |
Note | For research use only |
> 98% (HPLC) | |
1316695-35-8 | |
229.2 | |
C11H8FN5 |