LM-021

SKU: orb3133786

Description

LM-021, a coumarin-chalcone derivative, exhibits properties such as anti-aggregation, antioxidant, neuroprotective, and anti-inflammatory effects. It inhibits the production of nitric oxide (NO), IL-1β, IL-6, and TNF-α, as well as the expression of CD68 and MHCII. Additionally, LM-021 reduces caspase 1 activity, lactate dehydrogenase release, and ROS level elevation. It is used in neurological research.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 1022282-98-9
• MW: 335.35
• Formula: C₂₀H₁₇NO₄
• SMILES: OC=1C=2C(OC(=O)C1C(/C=C/C3=CC=C(N(C)C)C=C3)=O)=CC=CC2
• Target: Interleukin,Dehydrogenase,Reactive Oxygen Species,Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Interleukin,Dehydrogenase,Reactive Oxygen Species,Caspase