Lithocholic amide-C2-N(didecane)

SKU: orb3174552

Description

Lithocholic amide-C2-N(didecane) (Compound LC10) is a derivative of lithocholic acid. This compound spontaneously forms lipid nanoparticles in aqueous environments, allowing it to penetrate the skin and reach the dermis, where it exerts anti-inflammatory effects on psoriasis-like chronic skin inflammation. Lithocholic amide-C2-N(didecane) inhibits abnormal keratinocyte proliferation, downregulates the mRNA expression of the psoriasis-related receptor EphA2, and reduces serum levels of various pro-inflammatory factors (such as IL-1α, IL-1β, and IFN-γ) by inhibiting the activation of the Th17/Th2 inflammatory pathways.

Key Properties

• CAS Number: 2768690-22-6
• MW: 699.21
• Formula: C₄₆H₈₆N₂O₂
• SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCCN(CCCCCCCCCC)CCCCCCCCCC)=O)C)[H])[H]
• Target: Ephrin Receptor,Interleukin,IFNAR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Ephrin Receptor,Interleukin,IFNAR