Lirinidine

SKU: orb1297301

Description

Lirinidine is a natural alkaloid from L. tulipifera leaves with demonstrated antioxidant and anticancer properties in vitro. Its moderate iron-reducing and radical scavenging capacities support its investigation in cosmetic research and broader pharmacological studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 54383-28-7
• MW: 281.35
• Purity: 99.54% (May vary between batches)
• Formula: C₁₈H₁₉NO₂
• SMILES: [H][C@@]12Cc3ccccc3-c3c(O)c(OC)cc(CCN1C)c23
• Target: Antioxidant
• Solubility: DMSO:55 mg/mL (195.49 mM)

Bioactivity

• In Vitro:
  Sixteen compounds were extracted and purified from the leaves of Liriodendron tulipifera. These compounds include aporphines, oxoaporphine, coumarin, sesquiterpene lactone, benzenoids, cyclitol and steroids. (+)-Norstephalagine (2) (an aporphine) and scopoletin (8) (a coumarin) were isolated from Liriodendron tulipifera leaves from the first time. The identified compounds were screened for their antiradical scavenging, metal chelating and ferric reducing power activities. The results have showed that these compounds have antioxidative activity. The study has also examined the chemopreventive property of the isolated compounds against human melanoma cells A375. The results showed that (-)-anonaine (1), (-)-liridinine (3), (+)-Lirinidine (6), lysicamine (7) and epitulipinolide diepoxide (9) significantly inhibited the proliferation of melanoma cells
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cosmetic, anticancer, antioxidant, (+)-Lirinidine, PAFR, inhibit, Lirinidine, Inhibitor, ferric reducing, radical scavenge

Compound Identifiers

PubChem CID

31069