Lipid U 105

SKU: orb3026221

Description

Lipid U 105, an ionizable cationic lipid (pKa = 6.65), is employed in formulating lipid nanoparticles (LNPs) for delivering circular RNA both in vitro and in vivo. These LNPs, containing lipid U 105 and circular RNA for VEGF-A, enhance VEGF-A levels, boosting the proliferation and migration of human umbilical vein endothelial cells (HUVECs). Moreover, applying these LNPs topically accelerates wound healing in diabetic mice on a high-fat and -sugar diet.

Research Area

Metabolism Research

Key Properties

• CAS Number: 3049129-14-5
• MW: 867.42
• Formula: C₅₃H₁₀₆N₂O₆
• SMILES: O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCN(CCCN(CCO)CCO)CCCCCC(=O)OC(CCCCCCCC)CCCCCCCC
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others