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Lipid TD5

SKU: orb3138070

Description

Lipid TD5, an ionizable cationic lipid (pKa = 7.3), is utilized in the creation of lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. These LNPs are internalized via endocytosis in a serotonin (5-HT) receptor subtype 1A-dependent manner in primary mouse astrocytes. When administered intrathecally, LNPs containing lipid TD5 preferentially target the brain over the liver and spleen in mice.

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TargetOthers

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Lipid TD5 (orb3138070)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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