Lipid MK16

SKU: orb3033111

Description

MK-16 is a specialized lipid designed to traverse the blood-brain barrier (BBB) for effective mRNA delivery. Its formulation, MK 16 BLNP, leverages dual mechanisms involving caveolae and γ-secretase to facilitate BBB penetration, ensuring the targeted and efficient transport of functional mRNA to diverse brain cell types. Demonstrating excellent tolerability across a range of dosing regimens, MK16 BLNP represents a promising platform for brain-targeted therapeutic applications.

Research Area

Metabolism Research

Key Properties

• MW: 997.84
• Purity: >98%
• Formula: C₅₅H₉₁ClF₂N₂O₇S
• SMILES: CC(OCCCCCC)OCCCCCCN(CCCCCCOC(C)OCCCCCC)CCCCCCNC(CC[C@H]1CC[C@@](C2=CC(F)=CC=C2F)(S(C3=CC=C(Cl)C=C3)(=O)=O)CC1)=O

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only