Lipid I97

SKU: orb3026226

Description

Lipid I97 is an ionizable cationic lipid derived from vitamin B5 with a pKa of 6.23. It has been utilized in the formation of lipid nanoparticles (LNPs) for mRNA delivery in vivo. In mice, LNPs with lipid I97 encapsulating luciferase mRNA specifically accumulate in the spleen and lymph nodes. Additionally, LNPs containing lipid I97 with mRNA encoding hemagglutinin A trigger the production of IgG1 and IgG2 in mice.

Research Area

Metabolism Research

Key Properties

• CAS Number: 3046404-81-0
• MW: 967.41
• Formula: C₅₅H₁₀₂N₂O₁₁
• SMILES: [C@H](C(COC(CCCC(OCC(CCCCCCCC)CCCCCC)=O)=O)(C)C)(OC(CCCC(OCC(CCCCCCCC)CCCCCC)=O)=O)C(NCCC(OCCN(C)C)=O)=O
• Target: Others,Liposome

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others,Liposome