Linderalactone

SKU: orb1301270

Description

Linderalactone is a bioactive small molecule that potently inhibits fMLP/CB-induced superoxide anion generation in human neutrophils, with an IC50 of 8.48 µg/mL. This activity supports its research use in studying inflammatory pathways and oxidative stress in both cellular and animal models of neutrophil-mediated diseases.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 728-61-0
• MW: 244.29
• Purity: 99.79% (May vary between batches)
• Formula: C₁₅H₁₆O₃
• SMILES: [H][C@]12OC(=O)C(CC\C=C(C)\Cc3occ(C)c13)=C2
• Target: JAK,Apoptosis
• Solubility: DMSO:55 mg/mL (225.14 mM);10% DMSO+90% Corn Oil:2.5 mg/mL (10.23 mM)

Storage & Handling

• Storage: keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Linderalactone, Apoptosis

Compound Identifiers

PubChem CID

6450191