Lincomycin hydrochloride

SKU: orb1223835

Description

Lincomycin hydrochloride(Lincocin) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.Lincomycin is an antibiotic used to treat a wide variety of bacterial infections. It has been structurally modified by thionyl chloride to its more commonly known 7-chloro-7-deoxy derivative, clindamycin.(In Vivo):Lincomycin (25 and 50 mg/kg, intravenously) depresses neuromuscular transmission to a degree which depended on stimulation frequencies in the rabbit sciatic nerve-gastrocnemius muscle preparation.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 859-18-7
• MW: 443
• Purity: >98% (HPLC)
• Formula: C₁₈H₃₄N₂O₆S·HCl
• SMILES: CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O.Cl
• Target: ribosome
• Solubility: Water: 89 mg/mL (200.9 mM); DMSO: 89 mg/mL (200.9 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antibiotic 124a HCl, Lincomycin HCl, Lincomycin hydrochloride anhydrous, Mycivin

Quick Database Links

Gene Symbol

ribosome