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Linaclotide

SKU: orb1309479

Description

Linaclotide is a potent and selective agonist of the guanylate cyclase-C (GC-C) receptor, developed to treat IBS-C and chronic idiopathic constipation. It is widely used in gastrointestinal research to study receptor activation, fluid secretion, and motility in both cellular assays and animal models of functional bowel disorders.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetGuanylate cyclase
CAS Number851199-59-2
MW1526.74
Purity97.93% (May vary between batches)
FormulaC59H79N15O21S6
SMILESC[C@@H](O)C1NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CSSC[C@H](NC(=O)CNC1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC3=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Linaclotide, Inhibitor, Guanylate Cyclase, Guanylatecyclase, Guanylate cyclase

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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Linaclotide (orb1309479)

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Available Sizes

Select a size below

1 mg
$ 90.00
5 mg
$ 150.00
10 mg
$ 240.00
1 ml x 10 mM (in DMSO)
$ 330.00
25 mg
$ 390.00
50 mg
$ 560.00
100 mg
$ 780.00
200 mg
$ 1,030.00
DispatchUsually dispatched within 3-5 working days
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