Ligupurpuroside B

SKU: orb1684457

Description

Ligupurpuroside B is a phenethyl glycoside natural product isolated from Ligustrum robustum. It demonstrates antioxidant activity, as evidenced by an IC50 of 80.4 μM in an AAPH-induced erythrocyte haemolysis assay, supporting its research use in oxidative stress studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 147396-02-9
• MW: 738.74
• Purity: 99.95% (May vary between batches)
• Formula: C₃₅H₄₆O₁₇
• SMILES: CC1OC(OC2C(C)OC(OC3C(O)C(OCCc4ccc(O)cc4)OC(CO)C3OC(=O)C=Cc3ccc(O)cc3)C(O)C2O)C(O)C(O)C1O |w:33.34|
• Target: Antioxidant

Bioactivity

• In Vitro:
  According to Stern-Volmer equation, fluorescence of lipase was quenched by Ligupurpuroside B via a static quenching mechanism because of formation of Ligupurpuroside B-lipase complex. Binding constants, number of binding sites & thermodynamic parameters were evaluated. The values of ΔGo (-25.085 kJ mol-1), ΔHo (-12.14 kJ mol-1) and ΔSo (+43.45 J mol-1 K-1) at 298 K indicated that Ligupurpuroside B-lipase interaction is spontaneous and hydrophobic interaction is the main force stabilizing the Ligupurpuroside B-lipase complex. The enzyme activity assay showed that Ligupurpuroside B inhibited lipase activity efficiently. Synchronous fluorescence spectra (SFS) suggested that Ligupurpuroside B is closer to Trp residues than to Tyr residues.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ligupurpuroside B, LDL

Compound Identifiers

PubChem CID

131848455