Ligritinib

SKU: orb3135210

Description

Ligritinib (AB801) is an orally active inhibitor of the AXL receptor tyrosine kinase. By inhibiting the kinase activity of AXL, Ligritinib blocks its downstream signaling pathways. It is utilized in cancer research, particularly in studies involving non-small cell lung cancer (NSCLC) in combination with chemotherapy.

Research Area

Signal Transduction

Key Properties

• CAS Number: 3024588-48-2
• MW: 528.65
• Formula: C₃₃H₃₂N₆O
• SMILES: CC1=C(C2=CC=C(C=3C4=CC(C=5C=C6CC[C@@H](N7C8CC7COC8)CCC6=CC5)=CN=C4NN3)N=C2)N=CC=C1
• Target: TAM Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

TAM Receptor