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Liensinine

SKU: orb1222452

Description

Liensinine is a novel autophagy/mitophagy inhibitor.

Images & Validation

Key Properties

CAS Number2586-96-1
MW610.75
Purity>98% (HPLC)
FormulaC37H42N2O6
SMILESCN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)O)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)OC)O)OC
TargetOthers
SolubilityIn Vitro: DMSO : 50 mg/mL (81.87 mM)

Bioactivity

In Vivo
Animal model: KM mice. Dosage: 100 mg/kg, 200 mg/kg. Administration: oral gavage, daily, 10 weeks. Result: Reduced the gingival index and increased the SOD levels, the CAT, GSH-Px levels and decreased the NO, MDA, and ET levels compared to the control group. Animal model: Institute of Cancer Research (ICR) mice (male, 20-22 g). Dosage:. Administration: 5 mg/kg by oral administration; 1 mg/kg by intravenous administration. Result: The pharmacokinetic parameters of Liensinine in mice.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Liensinine |

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Liensinine (orb1222452)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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200 mg
500 mg
5 mg
$ 90.00
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25 mg
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100 mg
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