Licorice-saponin H2

SKU: orb1297179

Description

Licoricesaponin H2 is a natural triterpenoid saponin isolated from licorice root. It is utilized in biochemical research, with studies investigating its potential anti-inflammatory and hepatoprotective activities in both cellular and animal models.

Key Properties

• CAS Number: 118441-85-3
• MW: 822.93
• Purity: 99.76% (May vary between batches)
• Formula: C₄₂H₆₂O₁₆
• SMILES: [H][C@@]1(O[C@@H]2[C@@H](O)[C@H](O)[C@H](O[C@@]2([H])O[C@H]2CC[C@@]3(C)[C@@]([H])(CC[C@]4(C)[C@]3([H])C(=O)C=C3[C@]5([H])C[C@@](C)(CC[C@]5(C)CC[C@@]43C)C(O)=O)C2(C)C)C(O)=O)O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O
• Target: Others
• Solubility: DMSO:10 mM

Bioactivity

• In Vitro:
  Eight purified components from Glycyrrhiza, namely glabridin, glycyrrhetinic acid, glycyrrhizin, licochalcone A, Licoricesaponin H2 , licoricesaponin G2, liquiritigenin and liquiritin were evaluated for their antimutagenicity against MNU in the Ames assay with S. typhimurium TA1535. Glycyrrhetinic acid, glycyrrhizin, licoricesaponin G2, Licoricesaponin H2 and liquiritin did not show the antimutagenicity against MNU in S. typhimurium TA1535. Glabridin, licochalcone A and liquiritigenin reduced revertant colonies derived from MNU in S. typhimurium TA1535 without showing cytotoxic effects, indicating that these compounds possess antimutagenic activity against MNU. The inhibitory activity of glabridin and licochalcone A was more effective than that of liquiritigenin.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(18β,20α)-Glycyrrhizic acid, inhibit, Licorice saponin H2, Licoricesaponin H2, Licorice-saponin H2, Licorice-saponin H-2, Inhibitor, oligoglycoside, triterpene

Compound Identifiers

PubChem CID

12889143