Levofloxacin hydrate

SKU: orb1308581

Description

Levofloxacin hydrate

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 138199-71-0
• MW: 370.38
• Purity: 98.56%
• Formula: C₁₈H₂₀FN₃O₄·1/2H₂O
• SMILES: O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O
• Target: DNA gyrase,Antibiotic,DNA/RNA Synthesis,Antibacterial,Topoisomerase,Virus Protease
• Solubility: Ethanol:10 mg/mL (27 mM);H2O:5 mg/mL (13.5 mM);DMSO:50 mg/mL (135 mM);Methanol:10 mM

Bioactivity

• Cell Research:
  Cell suspension Samples (50 mL) (2-5×104 mast cells in Each tube for dispersed skin cells or 1 ×105 mast cells in Each tube for rat peritoneal cells) in duplicate are equilibrated at 37℃or 10 min, and then added to polypropylene tubes containing 450 mL test compounds dissolved in Tyrode solution. Histamine release reaction is allowed to proceed for a further 30 min. a the end of which tim the reaction is terminated by adding 2 ml ice-cold Tyrode solution an the mixture is centrifuged (450 g for 5 min at 4℃). For determination of total histamine content, mast cells are disrupted in boiling water for 10 min. Histamine concentration in the resulting supernatant and disrupted cells are determined b the enzyme immunoassay described above. (Only for Reference)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

airway inflammation, Antibiotic, Bacterial, BK Viremia, DNA/RNA Synthesis, DNA gyrase, DNAgyrase, Cravit hydrate, Cravit Hydrate, chronic periodontitis, Inhibitor, Levaquin hydrate, Levaquin Hydrate, Levofloxacin, Levofloxacin Hemihydrate, Levofloxacin Hydrate, Levofloxacin hydrate, Iquix Hydrate, Iquix hydrate, inhibit, Quixin Hydrate, Quixin hydrate, Topo IV, Topo II, Topoisomerase, Tavanic Hydrate, Tavanic hydrate

Compound Identifiers

PubChem CID

3033924