Levocetirizine Dihydrochloride

SKU: orb1704819

Description

Levocetirizine Dihydrochloride

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 130018-87-0
• MW: 461.81
• Purity: 99.89%
• Formula: C₂₁H₂₇Cl₃N₂O₃
• SMILES: O=C(O)COCCN1CCN([C@@H](C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1.Cl.Cl
• Target: Histamine Receptor
• Solubility: H2O:90 mg/mL (194.89 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.33 mM);DMSO:50 mg/mL (108.27 mM)

Bioactivity

• In Vivo:
  Levocetirizine (0.4 mg/kg; oral administration; Male Sprague Dawley rats) yields a Cmax of 0.34 μg/ml, an AUC0-t of 3.26 μg h/mL, an AUC0-∞ of 3.67 μg h/mL, and a t1/2 of 2.34 hours in Sprague Dawley rat.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

Cetirizine Dihydrochloride, Cetirizine, (-)-Cetirizine Dihydrochloride, HistamineReceptor, Histamine Receptor, Levocetirizine, Levocetirizine Dihydrochloride, H1 receptor, Xyzal, Xyzal Dihydrochloride

Compound Identifiers

PubChem CID

9955977