Leupeptin Hemisulfate

SKU: orb1227098

Description

Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases.

Key Properties

• CAS Number: 103476-89-7
• MW: 475.59
• Purity: >98% (HPLC)
• Formula: C₂₀H₃₈N₆O₄·1/2H₂SO₄
• SMILES: CC(C)C[C@@H](C(N)=O)N(C([C@H](CC(C)C)NC(C)=O)=O)[C@H](C=O)CCCNC(N)=N.CC(C)C[C@@H](C(N)=O)N(C([C@H](CC(C)C)NC(C)=O)=O)[C@H](C=O)CCCNC(N)=N.O=S(O)(O)=O
• Target: Cysteine Protease
• Solubility: Ethanol: 95 mg/mL (199.75 mM); Water: 95 mg/mL (199.75 mM); DMSO: 95 mg/mL warmed (199.75 mM)

Bioactivity

• In Vivo:
  Animal model: C57BL/6NCrl male mice (6-8 weeks old, 20-25 g). Dosage: 0, 9, 18, 36 mg/kg. Administration: Intraperitoneal injection; single. Result: Promoted the accumulation of LC3b-II in mouse liver.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Acetyl-L-leucyl-L-leucyl-L-argininal

Quick Database Links

Gene Symbol

Cysteine Protease