Leriglitazone hydrochloride

SKU: orb1983413

Description

Leriglitazone hydrochloride is a metabolite of pioglitazone that functions as a PPARγ agonist, stabilizing the AF-2 surface to enhance co-activator recruitment with a K i of 1.2 μM and an EC 50 of 680 nM. This compound is a valuable research tool for studying PPARγ-mediated transcriptional regulation in metabolic and inflammatory disease models, both in vitro and in vivo.

Research Area

Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 146062-46-6
• MW: 408.90
• Formula: C₁₉H₂₁ClN₂O₄S
• SMILES: Cl.CC(O)c1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
• Target: PPAR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

86748889