LEP(116-130)(mouse)

SKU: orb1296667

Description

LEP(116-130)(mouse)

Key Properties

• CAS Number: 258276-95-8
• MW: 1560.73
• Purity: 100.00%
• Formula: C₆₄H₁₀₉N₁₉O₂₄S
• SMILES: CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(N)=O
• Target: Others
• Solubility: DMSO:10 mM

Bioactivity

• In Vivo:
  Administration of LEP-(116-130) (1 mg, i.p.) results in decreased body weight gain, even with increased food consumption relative to Vehicle-injected control mice. It significantly reduces blood glucose levels by approximately 100 mg/dL. however, in wild-type (+/+) C57BLKS/J-m mice, LEP-(116-130) does not affect thermoregulation over 4 or 7 day.
• In Vitro:
  LEP-(116-130) (300 µM) fails to inhibit AP-OB binding and does not activate OB-Rb signal transduction in vitr.

Storage & Handling

• Storage: keep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

LEP, LEP(116 130)(mouse), LEP(116130)(mouse), LEP(116-130)(mouse), inhibit, Inhibitor

Compound Identifiers

PubChem CID

90471193