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LE01 Antibody

LE01 Antibody

Catalog Number: orb2803453

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Product Properties
Catalog Numberorb2803453
CategorySmall Molecules
DescriptionLE01 is a component of the antibody-drug conjugate (ADC) known as a drug-linker conjugate for ADC. It comprises an ADC linker and the DNA topoisomerase I inhibitor DXd. LE01 is used in the synthesis of the HER2-targeting antibody-drug conjugate named HER2-LE01.
TargetDrug-Linker Conjugates for ADC,Topoisomerase
MW1105.13
CAS Number2718125-83-6
FormulaC55H61FN10O14
SMILESN(C(COC(N(CCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(=O)C=CC2=O)=O)=O)=O)=O)=O)C)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Research AreaMolecular Biology
NoteFor research use only
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