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LDC4297

SKU: orb1690539

Description

LDC4297 is a potent and selective small molecule inhibitor of CDK7. It is a valuable research tool for investigating transcriptional regulation and cell cycle progression in both in vitro biochemical assays and in vivo cancer models.

Research Area

Cell Biology, Infectious Disease & Virology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number1453834-21-3
MW432.52
Purity98.25% (May vary between batches)
FormulaC23H28N8O
SMILESCC(C)c1cnn2c(NCc3ccccc3-n3cccn3)nc(OC3CCCNC3)nc12
TargetCDK,HIV Protease,HSV
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.62 mM);DMSO:60 mg/mL (138.72 mM)

Bioactivity

Target IC50
CDK7:0.13 nM|HSV2:0.27 μM (EC50)|HSV1:0.02 μM (EC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, LDC 044297, LDC 4297, LDC044297, LDC-044297, LDC4297, LDC-4297, Inhibitor, Herpes simplex virus, HSV, Cyclin dependent kinase, CDK7, CDK

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

LDC4297 (orb1690539)

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% DMSO +
%+
% Tween 80 +
%

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1 mg
$ 90.00
DispatchUsually dispatched within 3-5 working days
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