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LC3B recruiter 2

SKU: orb2944399

Description

LC3B recruiter 2 (34R) is an Autophagy-Tethering Compound (ATTEC) that binds LC3B and links to the CDK9 inhibitor SNS-032, enabling targeted degradation of the CDK9/Cyclin T1 complex via the autophagy-lysosome pathway. This bifunctional molecule inhibits and degrades its target, disrupting cancer cell cycle progression, and has demonstrated antitumor activity in cellular research models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number380636-64-6
MW224.644
FormulaC10H9ClN2O2
SMILESO=C1NC2=CC(Cl)=CC=C2C(=O)N1CC
TargetAutophagy,ATG,ATTECs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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LC3B recruiter 2 (orb2944399)

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