LC3B recruiter 2

SKU: orb2944399

Description

LC3B recruiter 2 (34R) is an Autophagy-Tethering Compound (ATTEC) that binds LC3B and links to the CDK9 inhibitor SNS-032, enabling targeted degradation of the CDK9/Cyclin T1 complex via the autophagy-lysosome pathway. This bifunctional molecule inhibits and degrades its target, disrupting cancer cell cycle progression, and has demonstrated antitumor activity in cellular research models.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 380636-64-6
• MW: 224.644
• Formula: C₁₀H₉ClN₂O₂
• SMILES: O=C1NC2=CC(Cl)=CC=C2C(=O)N1CC
• Target: Autophagy,ATG,ATTECs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

115587402