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LC-1-40

SKU: orb3133902

Description

LC-1-40 is a PROTAC that selectively degrades NUDT1 (DC50=0.97 nM). In mouse models, LC-1-40 selectively inhibits tumor growth induced by MYCN and induces nucleotide damage and apoptosis (cell death) in MYCN-associated tumors. It is applicable for cancer research.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

FormulaC49H48N8O6
TargetApoptosis,DNA/RNA Synthesis,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information