LB244

SKU: orb2277728

Description

LB244 is an orally bioavailable small molecule STING inhibitor with an EC50 of 0.8 µM. It is a functional analogue of BB-Cl-amidine, useful for studying STING-driven inflammation in cellular assays, though its oral bioavailability in mouse models is limited.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 3074622-05-9
• MW: 537.57
• Formula: C₃₀H₂₇N₅O₅
• SMILES: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C3=NC4=CC=CC=C4N3)CCCCNC(C5=CC=C([N+]([O-])=O)O5)=O
• Target: STING

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168679716