Lazabemide hydrochloride

SKU: orb1301592

Description

Lazabemide hydrochloride is a potent, reversible, and selective inhibitor of monoamine oxidase B (MAO-B) with a Ki of 7.9 nM. It is a valuable research tool for studying MAO-B's role in neurological disorders and has been utilized in both in vitro enzyme assays and in vivo models of Parkinson's disease.

Research Area

Metabolism Research, Neuroscience

Key Properties

• CAS Number: 103878-83-7
• MW: 236.098
• Purity: 99.56% (May vary between batches)
• Formula: C₈H₁₁Cl₂N₃O
• SMILES: Cl.NCCNC(=O)c1ccc(Cl)cn1
• Target: Monoamine Oxidase,MAO
• Solubility: DMSO:40 mg/mL (169.42 mM)

Bioactivity

• Target IC50:
  MAO-B:7.9 nM(ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DOPAC, disease, alzheimer′s, inhibit, N-(2-Aminoethyl)-5-chlor-2-pyridincarbox, parkinson, MonoamineOxidase, Monoamine Oxidase, MAO, MAO-B, Lazabemide, Lazabemide Hydrochloride, Lazabemide hydrochloride, Inhibitor, ichemia, radical generation, smoking cessation, Ro 19-6327

Compound Identifiers

PubChem CID

163727